Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neutropenic enterocolitis.

Marta L Davila1

  • 1Department of Gastrointestinal Medicine and Nutrition, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 436, Houston, TX 77030-4009, USA. mdavila@mdanderson.org.

Current Treatment Options in Gastroenterology
|August 12, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent Advancements in the Diagnosis and Treatment of Gastrointestinal Cancers.

Gastroenterology clinics of North America·2022
Same author

Outcome of EMR as an alternative to surgery in patients with complex colon polyps.

Gastrointestinal endoscopy·2016
Same author

Natural language processing as an alternative to manual reporting of colonoscopy quality metrics.

Gastrointestinal endoscopy·2015
Same author

Endoscopic management of Barrett's esophagus with high-grade dysplasia and early-stage esophageal adenocarcinoma.

Thoracic surgery clinics·2013
Same author

Optimum palliation of inoperable hilar cholangiocarcinoma: comparative assessment of the efficacy of plastic and self-expanding metal stents.

Digestive diseases and sciences·2011
Same author

Photodynamic therapy.

Gastrointestinal endoscopy clinics of North America·2010
Same journal

Esophageal Disorders in the Older Adult.

Current treatment options in gastroenterology·2025
Same journal

Endobariatrics: a Still Underutilized Weight Loss Tool.

Current treatment options in gastroenterology·2023
Same journal

Management of Post Ablative Barrett's Esophagus: a Review of Current Practices and Look at Emerging Technologies.

Current treatment options in gastroenterology·2023
Same journal

Inflammatory Bowel Disease Therapy and Venous Thromboembolism.

Current treatment options in gastroenterology·2023
Same journal

Ileal Pouch-Anal Anastomosis in the Older Adult: a Review of Postoperative Outcomes and Pouchitis Treatment.

Current treatment options in gastroenterology·2023
Same journal

Celiac Disease in the Elderly.

Current treatment options in gastroenterology·2023
See all related articles

Neutropenic enterocolitis, a severe GI complication of chemotherapy, requires prompt recognition. Management is individualized, typically starting conservatively with bowel rest and antibiotics, escalating to surgery for complications like perforation.

Area of Science:

  • Gastroenterology
  • Hematology
  • Oncology

Background:

  • Neutropenic enterocolitis (NE) is a critical gastrointestinal complication following chemotherapy, frequently seen in leukemia and lymphoma patients.
  • Early diagnosis and intervention are crucial for patient survival due to the high mortality rate associated with NE.

Purpose of the Study:

  • To review current understanding and management strategies for neutropenic enterocolitis.
  • To highlight the controversies and lack of high-quality evidence in NE treatment.

Main Methods:

  • Review of existing literature, including case studies and retrospective reports, due to the absence of prospective or high-quality retrospective research.
  • Analysis of common treatment approaches and indications for surgical intervention.

Related Experiment Videos

Main Results:

  • Management of NE is controversial, with no uniform strategy due to limited robust studies.
  • An individualized, case-specific approach is recommended, balancing conservative and surgical interventions.
  • Conservative management includes bowel rest, IV fluids, TPN, antibiotics, and neutrophil count normalization.

Conclusions:

  • Neutropenic enterocolitis necessitates an individualized treatment strategy.
  • Early conservative management is generally agreed upon, with surgery reserved for specific severe complications.
  • Further high-quality research is needed to establish definitive evidence-based guidelines for NE management.