Related Experiment Video
Updated: Aug 6, 2026

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods
Published on: April 14, 2023
Stability of andrographolide in powdered Andrographis herb under accelerated conditions
Anuchit Plubrukarn1, Sirirat Pinsuwan, Suthimaln Ingkatawornwong
1Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, Thailand.
Abstract:
The stability of andrographolide in powdered Andrographis Herb--the aerial part of Andrographis paniculata (Burm. f.) Nees (Acanthaceae)--was determined using a heat-accelerated experiment to reveal a second-order kinetics of degradation. The fast decomposition was observed regardless of the method of analysis. The rate constant of the decomposition of andrographolide at 25 degrees C ( K(25)( degrees C)), predicted from the Arrhenius plot, was 6.58 x 10 (-6) d (-1).
Related Concept Videos
Drug Product Stability
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention