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Updated: Aug 4, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
Published on: April 6, 2017
[Effect of aerosol therapy with cyclopheron in patients with chronic rhinitis]
Abstract:
Recently the number of patients with nasal cavity diseases has significantly increased mainly due to the chronic rhinitis. Due to the topical nature of the problem it is necessary to develop new methods of the treatment of chronic rhinitis and to use physiotherapeutic factors which have no side effects of chemotherapy. Total of 62 patients were investigated. 34 of these patients had chronic catarrhal rhinitis and 24 had chronic allergic rhinitis. It has been established that aerosol-therapy with cyclopheron has a considerable effect in patients with these forms of chronic rhinitis, right up to full normalization of their condition as well as on rhinoscopic data, particularly on the olfactory function and mucociliar clearance. Decrease of neutrophiles and eosinophiles present in the mucous discharged from the nasal cavity has a bacteriostatic action expressing in the decrease of size of colonies of microbial cultures.
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