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Biochemical Assays for Analyzing Activities of ATP-dependent Chromatin Remodeling Enzymes
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Mechanisms for nucleosome movement by ATP-dependent chromatin remodeling complexes

Anjanabha Saha1, Jacqueline Wittmeyer, Bradley R Cairns

  • 1Department of Oncological Sciences and Howard Hughes Medical Institute, Huntsman Cancer Institute, University of Utah School of Medicine, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.

Results and Problems in Cell Differentiation
|August 17, 2006
PubMed

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During mitosis, chromosome movements occur through the interplay of multiple piconewton level forces. In prometaphase, these forces help in chromosome assembly or congression at the equatorial plane, eventually leading to their alignment at the metaphase plate. The forces acting on the chromosomes are space and time-dependent; therefore, they vary with the position of the chromosomes as the cell progresses through mitosis. 
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