Related Experiment Video
Updated: Aug 6, 2026

06:09
Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Nutritional aspects of breath testing based on stable isotopes
M Dolores Parra1, J Alfredo Martínez
1Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain.
Nutrition Reviews
|August 17, 2006
Summary
Stable isotope 13C breath tests offer safe and effective nutritional assessments. These methods are increasingly used for evaluating metabolic processes due to technological advancements and reduced risks compared to radioactive tracers.
Area of Science:
- Biochemistry
- Nutritional Science
- Medical Diagnostics
Background:
- Stable isotope methodologies provide versatile tools for nutritional assessment.
- Advancements in mass spectrometry and reduced costs have increased the use of stable isotopes.
- Stable isotopes offer a safer alternative to radioactive tracers for metabolic studies.
Purpose of the Study:
- To review the application of carbon-13 (13C) breath tests for clinical and nutritional assessments.
- To highlight the advantages of using 13C as a stable isotope tracer.
- To discuss the growing importance of 13C breath tests in metabolic research.
Main Methods:
- Review of literature on stable isotope applications in nutrition.
- Focus on methodologies utilizing carbon-13 (13C) as a tracer.
- Analysis of 13C breath test applications in clinical and nutritional settings.
Main Results:
- 13C breath tests are a valuable tool for assessing metabolic pathways.
- The use of 13C offers advantages over traditional nutritional assessment methods.
- Technological progress has made 13C stable isotope tracing more accessible.
Conclusions:
- 13C breath tests are a powerful, non-invasive method for nutritional and clinical evaluation.
- Stable isotope techniques, particularly 13C breath tests, are expanding due to safety and technological factors.
- This review underscores the utility of 13C breath tests in understanding metabolic processes.
Related Concept Videos
Serum Laboratory Studies, Stool Test, Breath Test
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
Mass Spectrometry: Isotope Effect
Most elements exist in nature as a mixture of isotopes. The isotopes differ in weight due to their respective number of neutrons. The molecular weight of a molecule is different depending on the specific isotope of its elements involved. As a result, the mass spectrum of the molecule exhibits peaks from the same fragment at multiple positions. The positions of these mass signals depend on the mass differences between isotopes. Furthermore, the intensity of these signals is dependent on the...
Assessment of Diffusion and Perfusion
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

