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[Mathematical assessment of the blood prothrombinase-thrombin activity by the autocoagulation test]
Abstract:
A new method for estimation of the time course of prothrombinase-thrombin activity is suggested. The method is based on approximation of the autocoagulogram appropriate section to the regression straight line and estimation of the angular coefficient B. This coefficient more accurately reflects the rate of the prothrombinase-thrombin activity growth and decline. The method is time-saving and simple, it is recommended for estimation of functional activity of hemostasis major component and of the principal marker of thrombin formation, the blood disseminated intravascular coagulation.