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Updated: Aug 6, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
Multiple cerebral metastases mimicking Wernicke's encephalopathy in a chronic alcoholic
Ozgur Yaldizli1, Friedrich M Wurst, Sebastian Euler
1Psychiatric University Clinic, University of Basel, Wilhelm-Klein-Strasse 27, Basel, Switzerland.
Aims:
Alcohol dependent patients in withdrawal display a wide spectrum of neurological and neuropsychological symptoms that complicate diagnosis. We report the case of a 53-year-old male alcoholic with disorientation, ataxia and nystagmus in alcohol withdrawal probably due not to initial supposed Wernicke's encephalopathy (WE) but rather due to multiple cerebral metastases of a non-small cell cancer of the lung.
Results:
The findings illustrate the importance of initially maintaining a tentative attitude toward causation of symptoms and the role of brain imaging in formulating an accurate diagnosis.
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