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[The etiological structure of acute intestinal infections]
Abstract:
The share of various etiologic forms of acute intestinal infections, diagnosed by bacteriologic methods, is presented. The share of gastroenterocolitis induced by opportunistic microflora makes up 35.6%, that of dysentery 25.6%, salmonellosis 18.5%; mixed infection (dysentery + salmonellosis) is diagnosed in 7% of cases with acute intestinal infections. The principal representative of opportunistic microflora isolated from patients with acute intestinal infections is the Klebsiella genus (40.6%), whereas in the reference group Citrobacter, Morganella, and Klebsiella detection rates are approximately the same (27.0-18.3%). Opportunistic microorganisms in titers under 10(6) are isolated from normal subjects 5 times more frequently than from the patients, this indicating the diagnostic value of this level of feces contamination with opportunistic microflora.
Insights
Opportunistic microflora, particularly Klebsiella, is a significant cause of acute intestinal infections. Lower fecal opportunistic microorganism titers in healthy individuals suggest diagnostic value for these infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Diagnostics
Context:
- Acute intestinal infections (AIIs) pose a significant public health challenge.
- Bacteriologic methods are crucial for diagnosing the etiologic agents of AIIs.
- Understanding the role of opportunistic microflora in AIIs is essential for effective treatment.
Purpose:
- To present the distribution of various etiologic forms of acute intestinal infections.
- To identify the predominant opportunistic microflora in patients with AIIs.
- To evaluate the diagnostic significance of opportunistic microorganism titers in feces.
Summary:
- Gastroenterocolitis from opportunistic microflora accounts for 35.6% of AIIs, followed by dysentery (25.6%) and salmonellosis (18.5%).
- Mixed infections (dysentery + salmonellosis) occur in 7% of AII cases.
- Klebsiella is the main opportunistic pathogen in AII patients (40.6%), unlike in controls where Citrobacter, Morganella, and Klebsiella are equally prevalent.
- Opportunistic microorganisms in titers <10(6) are found 5 times more often in healthy individuals, indicating diagnostic value.
Impact:
- Provides data on the prevalence of different pathogens causing acute intestinal infections.
- Highlights the significant role of opportunistic microflora, especially Klebsiella, in AIIs.
- Suggests a potential diagnostic marker for AIIs based on opportunistic microorganism fecal titers.