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Ethyl vinyl chloride vapocoolant spray fails to decrease pain associated with intravenous cannulation in children
Mary Costello1, Maria Ramundo, Norman C Christopher
1Department of Pediatrics, Northeastern Ohio Universities College of Medicine, Rootstown, OH, USA.
Insights
Ethyl vinyl chloride vapocoolant spray did not reduce pain during intravenous cannulation in children. Pain scores were similar compared to isopropyl alcohol spray or no spray.
Area of Science:
- Pediatric Emergency Medicine
- Pain Management
- Anesthesiology
Background:
- Intravenous cannulation is a common procedure in pediatric emergency departments.
- Effective pain management during this procedure is crucial for patient comfort and cooperation.
- Vapocoolant sprays are used to provide localized cooling and reduce pain perception.
Purpose of the Study:
- To evaluate the efficacy of ethyl vinyl chloride vapocoolant spray in alleviating pain during intravenous cannulation in children.
- To compare the pain reduction effects of ethyl vinyl chloride spray against a placebo (isopropyl alcohol spray) and a control group (no spray).
Main Methods:
- A randomized, double-blinded, placebo-controlled trial was conducted.
- 127 children aged 9-18 years undergoing intravenous cannulation were enrolled.
- Participants were randomized to receive ethyl vinyl chloride spray, isopropyl alcohol spray, or no spray.
- Pain was assessed using a 100-mm visual analog scale (VAS).
Main Results:
- Mean VAS pain scores were 34 for ethyl vinyl chloride spray, 33 for isopropyl alcohol spray, and 31 for the control group.
- Ethyl vinyl chloride spray did not demonstrate a significant reduction in pain compared to the placebo or control group.
- No measurable difference in pain was observed between the intervention and control groups.
Conclusions:
- Ethyl vinyl chloride vapocoolant spray is not effective in reducing pain associated with intravenous cannulation in pediatric patients.
- Current evidence does not support the use of ethyl vinyl chloride spray for pain management during this procedure.
- Further research may explore alternative pain relief methods for pediatric intravenous cannulation.
Abstract:
The purpose of the study was to determine the effect of ethyl vinyl chloride vapocoolant spray on pain reported by children undergoing intravenous cannulation. A randomized, double-blinded, placebo-controlled trial was conducted on eligible children between the ages of 9 and 18 years seen in a pediatric emergency department and requiring intravenous cannulation. Informed consent was obtained, and children were randomized to receive ethyl vinyl chloride spray, isopropyl alcohol spray, or no spray (control group). Patient demographics and information pertaining to each intravenous cannulation were recorded. Children indicated the degree of pain associated with intravenous cannulation on a 100-mm visual analog scale (VAS) compared to a baseline pain score of "zero." Statistical analysis was performed by using Stata version 7. One hundred twenty-seven subjects were enrolled: 37 received ethyl vinyl chloride vapocoolant spray, 48 received isopropyl alcohol spray (placebo), and 42 received no pretreatment. Mean VAS scores for pain experienced during cannulation were 34, 33, and 31 mL for each group, respectively. Ethyl vinyl chloride vapocoolant spray failed to measurably reduce pain associated with intravenous cannulation when compared to those pretreated with isopropyl alcohol spray or receiving no intervention.
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