[Transformation and ultrastructural changes in erythrocytes in local hemolytic reactions]

Human and animal cell transformation in the local autoimmune hemolysis and stimulated erythrodieresis is enhanced during plaque formation, which fact is parallelled by a growing number of local hemolysis sites and increase of these sites' area in the preparations. Echino-poikilospherocytic transformation and ultrastructural changes in the red cells in these tests are explained by enhanced synthesis of autoantibodies-hemolysins by autoplaque-forming cells, as well as by the osmotic processes and destabilization of the cellular membrane system, including the leukocytic membranes.