Related Experiment Video
Updated: Jul 20, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
[Repair of recurrent cerebrospinal fluid rhinorrhea and skull base defect by endoscope]
Pinan Liu1, Yonghua Li, Fuqiang Ni
1Department of Neurosurgery, Affiliated Beijing Tiantan Hospital of Capital University of Medical Sciences, Beijing, 150001, China.
Objective:
To evaluate the failed causes of repairing the cerebrospinal fluid rhinorrhea and the use of endoscope techniques.
Method:
Eighteen cases with recurrent cerebrospinal fluid (CSF) rhinorrhea were retrospective studied.
Result:
Thirteen cases were repaired successfully at the first time transnasal endoscope and three cases succeed at the second attempt, two cases lost following-up after the failed repairing.
Conclusion:
Endoscopic repairing of CSF rhinorrhea is effective. The failure factors were: the leak location, repairing material and placement techniques, the area of skull base defect, correct localizing leak etc.
