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Updated: Jul 20, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Issues of antimicrobial resistance in group B streptococcus in the era of intrapartum antibiotic prophylaxis
1Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA. morvene@bcm.tmc.edu
Abstract:
The implementation of a culture screening-based approach to intrapartum antibiotic prophylaxis has been associated with substantial reduction in the incidence of early-onset group B streptococcal disease. Antibiotic prophylaxis is recognized as an interim strategy awaiting the licensure of a safe and effective conjugate vaccine for prevention of group B streptococcal infections in all susceptible populations. This article addresses concerns relating to antimicrobial resistance among group B streptococci that have arisen from use of intrapartum antibiotic prophylaxis and from increases in resistance in other gram-positive bacteria related genetically to group B streptococci.
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