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Related Experiment Videos

Handheld rectilinear ion trap mass spectrometer.

Liang Gao1, Qingyu Song, Garth E Patterson

  • 1Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.

Analytical Chemistry
|September 2, 2006
PubMed
Summary
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A new handheld mass spectrometer, Mini 10, offers portable chemical analysis with unit resolution and tandem mass spectrometry capabilities. This compact, battery-powered instrument enables in situ detection of airborne and dissolved compounds.

Area of Science:

  • Analytical Chemistry
  • Instrument Development
  • Mass Spectrometry

Background:

  • Mass spectrometry miniaturization is crucial for portable chemical analysis.
  • Rectilinear ion traps offer simplified geometry and high trapping capacity.
  • Previous research focused on experimental and simulation programs for miniaturized mass spectrometers.

Purpose of the Study:

  • To design, build, and characterize a shoebox-sized, handheld mass spectrometer.
  • To enable in situ chemical analysis with a portable instrument.
  • To demonstrate the capabilities of the Mini 10 for continuous monitoring.

Main Methods:

  • Development of a Mini 10 instrument based on a rectilinear ion trap mass analyzer.
  • Integration of a miniature and ruggedized pumping system for portability.

Related Experiment Videos

  • Implementation of compact electronics, including an air core RF drive coil, and battery power.
  • Utilizing collision-induced dissociation for tandem mass spectrometry.
  • Employing membrane sample introduction for air and solution analysis.

    • Main Results:

    • The Mini 10 achieved unit resolution and a mass range over m/z 500.
    • Tandem mass spectrometry confirmed chemical structures during in situ analysis.
    • Continuous monitoring of air and solution samples was demonstrated.
    • A limit of detection of 50 ppb was achieved for toluene vapor and aqueous naphthalene.

    Conclusions:

    • The Mini 10 is a viable handheld mass spectrometer for portable chemical analysis.
    • The instrument's design facilitates in situ analysis with high sensitivity.
    • The Mini 10 demonstrates potential for environmental monitoring and field applications.