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Guaianolides from Salvia nubicola (Lamiaceae)
Muhammad Shaiq Ali1, Waqar Ahmed, Andrea Florence Armstrong
1H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi, Pakistan. shaiq303@hotmail.com
Chemical & Pharmaceutical Bulletin
|September 2, 2006
Abstract:
A new sesquiterpene-lactone (nubenolide) belonging to the guaianolide class along with its acetate (nubenolide acetate) and a dimer (bisnubenolide) have been isolated from Salvia nubicola collected from Quetta, Pakistan. Structures of all three new metabolites were elucidated with the aid of spectroscopic techniques including 2D-NMR. However, the structure of nubenolide was finally confirmed via single-crystal X-ray diffraction method.