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Published on: June 4, 2017
Anxiety in allergy and atopic dermatitis
Hideo Hashizume1, Masahiro Takigawa
1Department of Dermatology, Hamamatsu University School of Medicine, Handa-yama, Hamamatsu, Japan. hihashiz@hama-med.ac.jp
Current Opinion in Allergy and Clinical Immunology
|September 7, 2006
Summary
Anxiety exacerbates allergic reactions, particularly atopic dermatitis, by disrupting immune responses. Managing psychological stress with anxiolytic treatments can effectively alleviate symptoms like itching in allergic individuals.
Area of Science:
- Psychoneuroimmunology
- Allergy Research
- Dermatology
Background:
- Allergic individuals often present with anxiety, depression, and emotional excitability.
- Emotional stress can trigger allergic symptoms by increasing anxiety and disrupting immune cell function.
Purpose of the Study:
- To review current research on the link between anxiety and hypersensitivity in allergic patients.
- Focus on atopic dermatitis and psychoneuroimmunology.
Main Methods:
- Literature review of psychoneuroimmunological studies.
- Analysis of the relationship between stress, anxiety, and immune responses in atopic dermatitis.
Main Results:
- A cycle exists where anxiety worsens clinical symptoms in atopic individuals.
- Chronic stress elevates anxiety, dysregulates the neuroimmune system, and promotes Th2-type responses, worsening allergic conditions.
- Anxiolytic medication (Tandospirone) reduced itching by managing emotional distress.
Conclusions:
- Psychological interventions, including anxiety monitoring, are crucial for managing allergic patients with emotional issues.
- Integrating immune function and skin condition assessments is vital for comprehensive therapy.
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