[Solid-phase immunoenzyme analysis of alpha-fetoprotein in human blood serum]

A test system for enzyme immunoassay of alpha-fetoprotein (AFP) was developed on the basis of the diagnostic agents manufactured by the N. F. Gamaleya Research Institute of Epidemiology and Microbiology. The effect of shielding antibody active centers in sensitization of planes with excessive concentrations of antibodies was detected. The test system was used to measure AFP levels in blood sera of pregnant women. The results may be used for screening pregnant women for the prenatal diagnosis of fetal neural tube.