Related Experiment Video
Updated: Jul 20, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
[Raynaud phenomenon in dermatology : Part 2: therapy]
C Sunderkötter1, G Riemekasten
1Klinik und Poliklinik für Dermatologie, Universitätsklinik Münster, Von-Esmarch-Strasse 58, 48129, Münster, Deutschland. cord.sunderkoetter@ukmuenster.de
Summary
Timely treatment for Raynaud phenomenon (RP), especially secondary RP linked to systemic sclerosis (SSc), is crucial. Prompt therapeutic intervention can prevent severe complications like ulcers and amputations.
Area of Science:
- Vascular Medicine
- Rheumatology
- Dermatology
Context:
- Primary Raynaud phenomenon (RP) rarely causes complications.
- Secondary RP, particularly when associated with systemic sclerosis (SSc), frequently leads to severe outcomes like necrosis and gangrene.
- Effective management of RP necessitates timely therapeutic intervention.
Purpose:
- To outline a strategic approach for managing Raynaud phenomenon (RP) based on disease severity and associated conditions.
- To detail specific pharmacological interventions for various RP presentations, including primary, secondary, and SSc-associated RP.
- To emphasize the importance of early treatment in preventing RP complications and potentially mitigating fibrotic processes.
Summary:
- Management strategies for RP include physical therapy, trigger avoidance, and medications.
- Suggested treatments range from calcium channel blockers for uncomplicated RP to targeted therapies like angiotensin-interfering drugs, serotonin reuptake inhibitors, iloprost, sildenafil, and bosentan for specific or severe cases.
- Off-label use of certain medications (c-f) is noted for recalcitrant cases or specific complications.
Impact:
- Timely therapy for SSc-associated secondary RP significantly reduces complications such as ulcers and amputations.
- Early intervention in RP may help retard the progression of associated fibrotic processes.
- This approach aims to improve patient outcomes and prevent digit loss in severe RP cases.
Related Concept Videos
01:27Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
01:26Peripheral Artery Disease IV: Nursing Management
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
01:18Disorders of the Autonomic Nervous System
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Raynaud's disease, also known as Raynaud's phenomenon, is a...
01:21Rheumatic Heart Disease III: Medical Management
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
01:26Varicose Veins II: Diagnostic Studies and Interprofessional Care
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
01:27Coronary Artery Disease V: Interprofessional Care
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...