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Updated: Jul 20, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
[About a case of common variable immunodeficiency--revision of hypogammaglobulinemias]
Alexandra Lopes1, Fernando Barata
1Serviço de Medicina do Centro Hospitalar de Coimbra, Quinta dos Vales, 2040 Coimbra.
Abstract:
Common variable immunodeficiency is a primary immune deficiency characterized by heterogeneous immunologic disorders of unknown etiology. Its clinical manifestations include recurrent infections, autoimmune diseases, lymphoid hyperplasia, granulomatous diseases and malignancy. It can appear in patients with immunoglobulin A deficiency. The authors report the clinical case of a patient with common variable immunodeficiency and history of respiratory infections from the age of 9 months old, associated with the appearing of bronchiectasis.
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