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Nuclear medicine imaging of diabetic foot infection: results of meta-analysis
Gabriela Capriotti1, Marco Chianelli, Alberto Signore
1Nuclear Medicine, II Faculty of Medicine, University of Rome La Sapienza, Rome, Italy.
Background And Aim:
Osteomyelitis of the foot is the most commonly encountered complication in diabetic patients. Nuclear medicine techniques are usually complementary to radiology in the diagnosis of foot infections; they play an important role in various clinical situations. The aim of this study was to develop a practical guideline to describe the radiopharmaceuticals to be used for different clinical conditions and different aims in diabetic foot infection.
Methods:
In this study, we reviewed 57 papers (published between 1982 and 2004; 50 original papers and seven reviews) that described the imaging of the diabetic foot and examined a total of 2889 lesions. We performed data analysis to establish which imaging technique could be used as a 'gold standard' to diagnose infection, evaluate the extent of disease and monitor the efficacy of therapy.
Results And Conclusion:
We provide a guideline to assist in the selection of the optimal radiopharmaceuticals for different clinical conditions and different aims.
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