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Updated: Jul 20, 2026
An Open-Source, Fully Customizable 5-Choice Serial Reaction Time Task Toolbox for Automated Behavioral Training of Rodents
Published on: January 19, 2022
Opening the adaptive toolbox
Janet Wittes1, Peter A Lachenbruch
1Statistics Collaborative, 1625 Massachusetts Ave., NW, Washington, DC 20036, USA. janet@statcollab.com
Abstract:
This is a discussion of the following three papers appearing in this special issue on adaptive designs: 'A regulatory view on adaptive/flexible clinical trial design' by H. M. James Hung, Robert T. O'Neill, Sue-Jane Wang and John Lawrence; 'Confirmatory clinical trials with an adaptive design' by Armin Koch; and 'FDA's critical path initiative: A perspective on contributions of biostatistics' by Robert T. O'Neill.
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