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Clinical evaluation of cornea pseudoguttata
Y Nakashima1, F Yoshitomi, T Oshika
1Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan.
The British Journal of Ophthalmology
|September 16, 2006
Summary
Cornea pseudoguttata, a condition affecting the cornea, was observed in 1.1% of patients. This finding indicates that cornea pseudoguttata is reversible and resolves without damaging corneal endothelial cells.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Cellular Biology
Background:
- Cornea pseudoguttata is a condition characterized by guttate changes in Descemet's membrane.
- Its occurrence and clinical significance in a large patient cohort warrant investigation.
Observation:
- Cornea pseudoguttata was identified in 44 eyes (1.1%) of 40 patients undergoing routine eye examinations.
- The condition was associated with various anterior segment ocular diseases, most commonly keratitis with contact lens wear.
Findings:
- In 38 eyes with follow-up, cornea pseudoguttata completely resolved as the primary ocular disease subsided.
- Specular microscopy post-resolution revealed no significant difference in corneal endothelial cell density between affected and healthy eyes.
Implications:
- Cornea pseudoguttata is a reversible finding, often associated with corneal inflammation and infiltration.
- Resolution of cornea pseudoguttata does not appear to cause lasting damage to corneal endothelial cells.
