Related Experiment Video
Updated: Jul 20, 2026

Interview: Glycolipid Antigen Presentation by CD1d and the Therapeutic Potential of NKT cell Activation
Published on: December 31, 2007
The therapeutic potential of CD39: interview with Dr Simon Robson by Emma Quigley
Abstract:
Dr Simon C Robson (Harvard University) was interviewed by Emma Quigley (Commissioning Editor, Expert Opinion) on 14th August 2006. Born in the UK, Dr Simon Robson obtained his MB, ChB from the University of Cape Town, South Africa in 1978 and his PhD in Immunology in 1989. He worked in both South Africa and the UK before moving to the USA in 1994. Now an Associate Professor in Medicine at Harvard University, Dr Robson is conducting research dealing with the vascular biology of transplantation and specifically focussing on how endothelial and immune cell purinergic signalling is modulated by ecto-nucleotidases of the CD39 family (ecto-enzymes that hydrolyse extracellular nucleotides to generate nucleosides). In several studies funded by the NIH, ROTRF and other agencies, Dr Robson has been researching genomics, proteomics and the biology of CD39 in models of inflammation and immunity. Dr Robson has published > 200 papers and is on the Editorial Boards of many well-respected journals, including Expert Opinion on Therapeutic Targets.
More Related Videos
08:46A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells
Published on: November 12, 2019
08:47Experimental Quantification of Interactions Between Drug Delivery Systems and Cells In Vitro: A Guide for Preclinical Nanomedicine Evaluation
Published on: September 28, 2022
Related Concept Videos
Therapeutic Communication
Verbal communication depends on language or a prescribed way of using words so that people can share information effectively. The critical aspects of verbal...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Therapeutic Drug Monitoring: Affecting Factors
Treatment Resistant Cancers
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...