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Long-term clinical outcome of patients with diabetes proposed for coronary revascularisation

J R Timmer1, A Breeman, J P Ottervanger

  • 1Department of Cardiology, Isala Klinieken, Zwolle, the Netherlands.

The Netherlands Journal of Medicine
|September 23, 2006
PubMed

Insights

Diabetic patients with coronary artery disease (CAD) face higher long-term mortality. Coronary artery bypass grafting offers comparable survival for diabetic patients, suggesting complete revascularization improves outcomes.

Area of Science:

  • Cardiology
  • Diabetology
  • Clinical Research

Background:

  • Optimal revascularization in diabetic patients with coronary artery disease (CAD) is debated.
  • Evaluating long-term outcomes in diabetic CAD patients undergoing invasive procedures is crucial.

Purpose of the Study:

  • To assess the long-term outcomes of diabetic patients with CAD in a real-world setting.
  • To compare the effectiveness of different revascularization strategies in this population.

Main Methods:

  • Prospective follow-up study of patients considered for coronary revascularization.
  • Vital status data collected up to ten years post-inclusion.

Main Results:

  • Diabetic patients (12%) had higher long-term mortality (36% vs. 25%).
  • Higher mortality in diabetics undergoing medical treatment or percutaneous coronary intervention.
  • No significant mortality difference between diabetic and non-diabetic patients after coronary artery bypass grafting (CABG).

Conclusions:

  • Diabetic patients with significant CAD experience increased long-term mortality.
  • CABG provides the best survival for diabetic patients, comparable to non-diabetic patients.
  • Complete revascularization may mitigate the negative impact of diabetes on survival.
Abstract

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