Related Experiment Video
Updated: Jul 19, 2026

Isolation and Cannulation of Cerebral Parenchymal Arterioles
Published on: May 23, 2016
Lhermitte-Duclos disease with cervical paraspinal arteriovenous fistula
Yukinori Akiyama1, Jun Ikeda, Yukihiro Ibayashi
1Department of Traumatology, Sapporo Medical University, Sapporo, Hokkaido, Japan. akiyuki@sapmed.ac.jp
Abstract:
A 38-year-old man presented with a dysplastic cerebellar gangliocytoma associated with a paraspinal arteriovenous fistula (AVF) at the upper cervical portion. Neuroimaging examination indicated the diagnosis of Lhermitte-Duclos disease. The patient was treated by embolization of the AVF followed by partial resection of the cerebellar tumor. Genetic examination showed a mutation of the phosphatase and tensin homolog deleted on chromosome ten (PTEN) gene. Histological examination confirmed the diagnosis. Lhermitte-Duclos disease is a rare dysplastic gangliocytoma manifesting as a slowly growing mass in the cerebellum and is usually asymptomatic. This case of Lhermitte-Duclos disease associated with paraspinal AVF and mutation of the PTEN gene suggests a relationship between Lhermitte-Duclos disease and Cowden disease.
Related Concept Videos
Herniated Intervertebral Disc l: Introduction
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Degenerative Disc Disease ll: Pathophysiology