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Updated: Jul 9, 2026

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An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
Published on: April 17, 2020
Transhiatal esophagectomy (THE)
Maria Letizia Vita1, Alessio Piraino, Adele Tessitore
1Dipartimento di Chirurgia Toracica, Università Cattolica del S. Cuore, Policlinico A.Gemelli, Roma, Italy. marialetiziavita@yahoo.it
Summary
Transhiatal esophagectomy (THE) offers lower morbidity than transthoracic approaches. Despite concerns about lymphadenectomy, THE is a viable option for esophageal cancer, with outcomes comparable to other methods.
Area of Science:
- Surgical Oncology
- Gastrointestinal Surgery
- Esophageal Cancer Treatment
Background:
- Transhiatal esophagectomy (THE) is a surgical technique for esophageal removal without thoracotomy.
- It involves abdominal and cervical approaches, pioneered by Orringer with extensive experience.
- THE is associated with lower morbidity compared to transthoracic esophagectomy.
Purpose of the Study:
- To evaluate the suitability of Transhiatal Esophagectomy (THE) for esophageal cancer.
- To compare the outcomes of THE with transthoracic approaches for esophageal cancer treatment.
- To analyze the role of surgical technique versus tumor biology in esophageal cancer prognosis.
Main Methods:
- Review of Transhiatal Esophagectomy (THE) technique and its application in esophageal cancer.
- Comparison of morbidity and survival data between THE and transthoracic esophagectomy.
- Analysis of factors influencing esophageal carcinoma outcomes, including tumor stage and systemic disease.
Main Results:
- THE demonstrates lower morbidity than transthoracic approaches.
- Controversy exists regarding THE's suitability for cancer due to lack of en-bloc lymphadenectomy.
- No significant statistical differences in overall outcomes were observed between THE and transthoracic approaches for esophageal cancer.
Conclusions:
- Transhiatal Esophagectomy (THE) is a viable surgical option for esophageal cancer, offering reduced morbidity.
- Tumor biology and stage are critical determinants of esophageal cancer prognosis, often outweighing surgical technique.
- Further research may clarify the role of lymphadenectomy in THE for specific cancer presentations.
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