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Updated: Aug 10, 2026

The Use of Flow Cytometry to Assess the State of Chromatin in T Cells
11:01

The Use of Flow Cytometry to Assess the State of Chromatin in T Cells

Published on: December 17, 2015

[Chromatin packing in the nuclei of mammalian cells studied by flow cytometry]

M V Filatov, E Iu Varfolomeeva

    Tsitologiia
    |January 1, 1990
    PubMed

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    Chromatin Packaging01:32

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    Each human somatic cell contains 6 billion base pairs of DNA. Each base pair is 0.34 nm long, meaning each diploid cell contains a staggering 2 meters of DNA. This long DNA strand is packed inside a nucleus measuring only 10-20 microns in diameter with the help of specialized DNA-binding proteins called histones. Together they form a compact DNA-protein complex called chromatin. The chromatin is further compacted into higher-order structures. The highest level of compaction is achieved during...