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Using Microfluidics and Fluorescence Microscopy to Study the Assembly Dynamics of Single Actin Filaments and Bundles
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Tropomodulin 3 binds to actin monomers.

Robert S Fischer1, Elena G Yarmola, Kari L Weber

  • 1Department of Cell Biology, The Scripps Research Institute, La, Jolla, California 92037, USA. bfischer@scripps.edu

The Journal of Biological Chemistry
|October 3, 2006
PubMed
Summary

Tropomodulin 3 (Tmod3) sequesters actin monomers, impacting cell migration. This protein binds actin monomers and filament ends, suggesting a unique regulatory mechanism distinct from other tropomodulins.

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