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Related Experiment Videos

Validating an asthma case detection instrument in a Head Start sample.

Sebastian Bonner1, Thomas Matte, Mitchell Rubin

  • 1Center for Urban Epidemiologic Studies, New York City Department of Health and Mental Hygiene, New York, NY 10029, USA. sbonner@nyam.org

The Journal of School Health
|October 10, 2006
PubMed
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A new 15-item Brief Respiratory Questionnaire (BRQ) effectively screens preschool children for probable asthma. This validated instrument aids early detection in high-risk communities, improving pediatric asthma management.

Area of Science:

  • Pediatric Pulmonology
  • Public Health
  • Medical Diagnostics

Background:

  • Asthma is a prevalent pediatric chronic condition, particularly in disadvantaged communities of color.
  • Existing screening tools lack validation for early asthma detection in preschool-aged children.
  • There is a critical need for validated instruments to identify children with probable asthma in early childhood settings.

Purpose of the Study:

  • To develop and validate the Brief Respiratory Questionnaire (BRQ) for detecting probable asthma in preschool children.
  • To assess the BRQ's accuracy and feasibility for use by nonmedical personnel in Head Start and subsidized preschools.
  • To provide a tool for early identification of asthma in high-prevalence, high-morbidity communities.

Main Methods:

Related Experiment Videos

  • A 15-item BRQ was developed and administered to parents of 419 children in Head Start settings.
  • A validation interview (VAL) was conducted with parents of 200 children (149 case-positive, 51 case-negative).
  • Physician assessments of summarized VALs served as the gold standard to compare BRQ classifications against.

    • Main Results:

    • A 4-item algorithm from the BRQ demonstrated good agreement with the validation standard (kappa = .73).
    • The 4-item BRQ algorithm achieved high specificity (96%), good sensitivity (73%), and a high positive predictive value (97%).
    • The BRQ can be administered and scored by nonmedical preschool staff in under 5 minutes.

    Conclusions:

    • The Brief Respiratory Questionnaire (BRQ) is a valid and efficient tool for identifying preschool children with probable asthma.
    • The BRQ is suitable for use in Head Start and similar subsidized preschool settings, particularly in underserved communities.
    • This validated screening instrument can facilitate timely intervention and management of pediatric asthma.