Related Experiment Video
Updated: Jul 19, 2026

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
Published on: January 21, 2018
Rhinosinusitis in children
1Department of Pediatrics, Ochsner Children's Health Center, 1315 Jefferson Highway, New Orleans, LA 70121, USA. RWSteele@aol.com
Insights
Updated guidelines are needed for pediatric acute bacterial rhinosinusitis due to changing antibiotic resistance. This review offers practical recommendations for managing chronic pediatric sinusitis, addressing various contributing factors.
Area of Science:
- Pediatrics
- Infectious Diseases
- Otolaryngology
Background:
- Existing 2001 guidelines for pediatric acute bacterial rhinosinusitis require updating.
- Changing antibiotic susceptibility patterns necessitate reevaluation of treatment recommendations.
- Previous guidelines inadequately addressed the pathogenesis and management of chronic pediatric sinusitis.
Purpose of the Study:
- To reevaluate and update clinical practice guidelines for pediatric rhinosinusitis.
- To provide specific recommendations and practical treatment options for pediatric chronic sinusitis.
- To address factors contributing to chronic rhinosinusitis in children.
Main Methods:
- Review of recent scientific literature.
- Synthesis of clinical experience from pediatric sinusitis experts.
- Identification of factors associated with chronic rhinosinusitis.
Main Results:
- Insufficient data exists for evidence-based guidelines for chronic pediatric sinusitis.
- Key factors associated with chronic rhinosinusitis include environmental pollution, viral infections, rhinitis, ciliary dyskinesia, cystic fibrosis, immunodeficiency, GERD, and anatomical abnormalities.
- Practical treatment options and expert recommendations are presented.
Conclusions:
- Current antibiotic susceptibility patterns warrant updated guidelines for acute bacterial rhinosinusitis.
- Individualized management addressing contributing factors is crucial for pediatric chronic sinusitis.
- Further research is needed to develop evidence-based guidelines for chronic pediatric sinusitis.
Abstract:
Clinical practice guidelines for the management of acute bacterial rhinosinusitis in children were published by the American Academy of Pediatrics in 2001. Changes in the antibiotic susceptibility patterns for the common pathogens causing both acute and chronic rhinosinusitis warrant a reevaluation and update of these recommendations. In addition, there was only a very brief discussion of chronic disease in this publication, with the conclusion that the pathogenesis and management of recurrent or prolonged infection were essentially unknown. Although there are still insufficient data in the literature to develop evidence-based clinical guidelines, a careful review of recent literature and the clinical experience of experts who manage pediatric chronic sinusitis are presented in an effort to provide some specific recommendations and to offer practical treatment options. Factors associated with chronic rhinosinusitis should be addressed individually and include environmental pollution, recurrent viral upper respiratory infections, allergic and nonallergic rhinitis, ciliary dyskinesia, cystic fibrosis, immunodeficiency, gastroesophageal reflux, and anatomic abnormalities.
Related Concept Videos
Respiratory Syncytial Virus Disease
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Microbiota of the Respiratory Tract
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...