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Clinical approach to the prostate: an update.
Alexander Kutikov1, Thomas J Guzzo, S Bruce Malkowicz
1Division of Urology, Department of Surgery, University of Pennsylvania Medical Center, 9 Penn Tower, 3400 Spruce Street, Philadelphia, PA 19104, USA. ak@post.harvard.edu
Radiologic Clinics of North America
|October 13, 2006
Summary
This review covers benign prostatic hyperplasia, prostate cancer, and prostatitis, highlighting current challenges and unanswered questions in their pathogenesis, diagnosis, and treatment efficacy for better patient outcomes.
Area of Science:
- Urology
- Andrology
- Medical Research
Background:
- Prostatic diseases, including benign prostatic hyperplasia (BPH), prostate cancer, and prostatitis, pose significant clinical challenges.
- Despite advancements, fundamental questions regarding BPH pathogenesis, progression, and treatment efficacy persist.
- Prostate cancer research continues to need progress, with ongoing debates on screening and therapeutic modalities.
Purpose of the Study:
- To review contemporary approaches to the pathogenesis, diagnosis, and treatment of key prostatic diseases.
- To address the persistent challenges and unanswered questions in managing BPH, prostate cancer, and prostatitis.
- To provide an overview of the current state of knowledge and future directions in prostatic disease management.
Main Methods:
- Literature review of current research and clinical practices.
- Analysis of contemporary approaches in pathogenesis, diagnosis, and treatment.
- Synthesis of information on benign prostatic hyperplasia, prostate cancer, and prostatitis.
Main Results:
- Significant challenges remain in understanding and treating prostatic diseases.
- Current treatment regimens for prostatitis are often ineffective.
- Debates continue regarding prostate-specific antigen screening and optimal therapeutic roles in prostate cancer.
Conclusions:
- Further research is crucial to address the gaps in knowledge for BPH, prostate cancer, and prostatitis.
- Development of more effective treatments for prostatitis is urgently needed.
- Resolving ongoing debates in prostate cancer management is essential for improved patient care.

