Folliculitis decalvans treated with radiation therapy

Area of Science:

• Dermatology
• Radiation Oncology

Background:

• Folliculitis decalvans is a rare, chronic, and inflammatory scalp condition characterized by recurrent pustules and painful folliculocentric lesions.
• It often leads to scarring alopecia and is notoriously difficult to treat with conventional therapies, including antibiotics and corticosteroids.

Observation:

• A 33-year-old African American male presented with severe, treatment-refractory folliculitis decalvans.
• The patient had failed multiple courses of oral and topical antibiotics, antifungals, and intralesional corticosteroids.

Findings:

• The patient was treated with a course of radiation therapy.
• Significant improvement in pustulation and inflammation was observed following radiation treatment.
• Complete resolution of active lesions and halting of disease progression were achieved.

Implications:

• Radiation therapy represents a novel and effective therapeutic option for severe, refractory folliculitis decalvans.
• This approach may offer a solution for patients who do not respond to established treatments.
• Further research into the efficacy and safety of radiation therapy for scalp inflammatory conditions is warranted.