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[Ultrasound diagnostics of atherosclerosis in chronic renal insufficiency]

Radojica Stolić1, Goran Trajković, Gordana Subarić-Gorgieva

  • 1Medicinski fakultet Pristina, 38220 Kosovska Mitrovica.

Medicinski Pregled
|October 17, 2006
PubMed

Insights

Atherosclerosis is common in hemodialysis patients, particularly those over fifty. Age and duration of dialysis are significant risk factors for atherosclerosis in this population.

Area of Science:

  • Nephrology
  • Cardiovascular Medicine
  • Vascular Biology

Background:

  • Atherosclerosis prevalence is elevated in individuals with chronic renal insufficiency compared to the general population.
  • Hemodialysis patients represent a high-risk group for cardiovascular complications, including atherosclerosis.

Purpose of the Study:

  • To determine the frequency of atherosclerosis in hemodialysis patients.
  • To identify risk factors associated with atherosclerosis in this cohort.

Main Methods:

  • A cohort of 62 hemodialysis patients (36 male, 26 female; mean age 56 ± 13 years) was assessed.
  • Evaluations included risk factor assessment, BMI, calcification analysis, and carotid artery Duplex ultrasonography.
  • Mean duration of hemodialysis was 65.7 ± 46.7 months.

Main Results:

  • Intima-media thickening, indicative of atherosclerosis, was observed in two-thirds of patients over fifty.
  • Atherosclerosis frequency did not significantly correlate with sex, calcification, plaque, smoking, or diabetes mellitus.
  • A significant correlation was found between atherosclerosis, patient age, and duration on hemodialysis.

Conclusions:

  • Age and prolonged duration on hemodialysis are significant predictors of atherosclerosis in hemodialysis patients.
  • Traditional risk factors showed no significant correlation with atherosclerosis severity in this study population.
  • Further research into non-traditional risk factors may be warranted for this patient group.
Abstract

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