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Updated: Jul 19, 2026
03:23
Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
[Extrafacial granuloma eosinophilicum]
A Rütten1, M Hantschke, B Schwarz
1Dermatopathologische Gemeinschaftspraxis, 88048, Friedrichshafen. ruetten@w-4.de
Summary
This study presents three cases of rare extrafacial granuloma eosinophilicum, a skin condition. Histopathology reveals distinct changes over time, from early vasculitis to later fibrotic changes.
Area of Science:
- Dermatology
- Pathology
Background:
- Granuloma eosinophilicum (GE) is a rare inflammatory skin condition.
- While typically facial, GE can present in extrafacial locations.
Observation:
- Three patients with rare extrafacial GE are presented.
- Lesions were located on the scalp, upper back, or upper arm.
- One patient also had a concurrent typical facial GE.
Findings:
- Diagnosis was confirmed via histopathology.
- Early lesions show vasculitis with eosinophils and a Grenz zone.
- Later lesions exhibit inflammation evolving into hyaline fibrosis.
Implications:
- This highlights the varied presentation of granuloma eosinophilicum beyond the face.
- Understanding histopathological progression is key for accurate diagnosis.
- Recognizing extrafacial GE aids in appropriate patient management.
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