Related Experiment Video
Updated: Jul 19, 2026

13:34
Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish
Published on: April 16, 2019
[Blood-tumor barrier in malignant brain tumor]
Yasuhiko Hayashi1, Yuya Yoshida, Jun-ichiro Hamada
1Department of Neurosurgery, Division of Neuroscience, Kanazawa Graduate School of Medical Science, Kanazawa University.
No Shinkei Geka. Neurological Surgery
|October 21, 2006
Abstract
No abstract available in PubMed .
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The Blood-brain Barrier
Overview
Physiological Barriers
Physiological barriers are semi-permeable cellular structures restricting drug diffusion into intracellular compartments and tissues. There are six types of physiological barriers: blood endothelial, cell membrane, blood-brain, blood-cerebrospinal fluid (CSF), blood-placenta, and blood-testis barriers.
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...