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Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes
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Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes

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Plasma membrane IP3 receptors

C W Taylor1, O Dellis

  • 1Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK. cwt1000@cam.ac.uk

Biochemical Society Transactions
|October 21, 2006
PubMed
Summary

Inositol 1,4,5-trisphosphate receptors (IP3Rs) function in the plasma membrane, mediating significant calcium (Ca2+) entry in DT40 cells. This Ca2+ influx via IP3Rs has distinct cellular effects compared to store-operated channels.

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