Purification and structural characterization of human ERp29.

Jinbiao Zheng1, Xingang Liu, Xiaomin Yan

  • 1Center of Analysis and Measurement, Fudan University, Shanghai 200433, PR China.

Summary

Human endoplasmic reticulum protein 29 (ERp29) has significant alpha-helical structure and is stable below 50°C. Temperature changes reveal two structural transitions, potentially explaining its limited ability to prevent protein aggregation.