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Design of a selective chemical probe for class I PDZ domains

Naoaki Fujii1, Anang Shelat, Randy A Hall

  • 1Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. naoaki.fujii@stjude.org

Bioorganic & Medicinal Chemistry Letters
|November 1, 2006
PubMed

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Labeling DNA Probes

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Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...