Related Experiment Video
Updated: Jul 19, 2026

04:12
Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
Published on: January 19, 2024
Topical treatments for melasma and postinflammatory hyperpigmentation.
Skin Therapy Letter
|November 1, 2006
Summary
Skin hyperpigmentation, including melasma and postinflammatory hyperpigmentation, causes distress. Sun protection and topical treatments like phenols, retinoids, and corticosteroids are key management strategies.
Area of Science:
- Dermatology
- Cosmetic Science
Background:
- Hyperpigmentation disorders are prevalent skin conditions.
- These conditions, such as melasma and postinflammatory hyperpigmentation, significantly impact patients' psychosocial well-being.
- Effective management is crucial for improving patient quality of life.
Purpose of the Study:
- To review the common hyperpigmentation disorders.
- To outline essential management strategies.
- To discuss current therapeutic options for skin hyperpigmentation.
Main Methods:
- Literature review of common hyperpigmentation disorders.
- Analysis of established treatment guidelines.
- Summary of topical therapeutic agents.
Main Results:
- Melasma and postinflammatory hyperpigmentation are the most frequent types.
- Sun avoidance and sunscreen use are fundamental preventative and management steps.
- Topical treatments including phenols, retinoids, and corticosteroids are the primary therapeutic approach.
Conclusions:
- Hyperpigmentation disorders require comprehensive management strategies.
- Sun protection is paramount for all patients.
- Combination topical therapies offer effective treatment options for skin hyperpigmentation.
Related Concept Videos
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Changes in Skin Color: Clinical Perspectives
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
