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Cost-effectiveness of impedance cardiography testing in uncontrolled hypertension
Carlos M Ferrario1, Ronald D Smith,
1Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. cferrari@wfubmc.edu
Insights
Impedance cardiography (ICG) testing is a cost-effective method for managing uncontrolled hypertension. This noninvasive approach offers significant short- and long-term benefits in reducing blood pressure and improving patient outcomes.
Area of Science:
- Cardiovascular Medicine
- Health Economics
Background:
- Uncontrolled hypertension poses significant health risks and economic burdens.
- Noninvasive hemodynamic monitoring strategies are being explored to optimize blood pressure management.
Purpose of the Study:
- To evaluate the short- and long-term cost-effectiveness of impedance cardiography (ICG) testing compared to standard care in patients with uncontrolled hypertension.
- To analyze data from the Consideration of Noninvasive Hemodynamic Monitoring to Target Reduction of Blood Pressure Levels (CONTROL) trial.
Main Methods:
- Short-term cost-effectiveness was assessed by the incremental cost per incremental mm Hg reduction in systolic and diastolic blood pressure.
- Long-term cost-effectiveness was evaluated using the incremental cost per quality-adjusted life-year (QALY) gained over a 10-year period.
- Comparison was made between ICG care and standard care groups.
Main Results:
- ICG care demonstrated superior short-term cost-effectiveness: $20/mm Hg for systolic BP (vs. $36 for standard care) and $23/mm Hg for diastolic BP (vs. $79 for standard care).
- Long-term analysis showed ICG resulted in $476 cost savings per patient and 0.109 QALYs gained.
- The incremental cost per QALY gained with ICG was -$4,371, with sensitivity analysis ranging from -$8,764 to $13,163.
Conclusions:
- Impedance cardiography testing is a cost-effective strategy for managing uncontrolled hypertension.
- ICG offers both immediate blood pressure reduction benefits and long-term improvements in patient quality of life and healthcare economics.
- The findings support the integration of ICG into clinical practice for hypertensive patients.
Abstract:
To evaluate the short- and long-term cost-effectiveness of impedance cardiography (ICG) testing in uncontrolled hypertensives, we analyzed the Consideration of Noninvasive Hemodynamic Monitoring to Target Reduction of Blood Pressure Levels (CONTROL) trial results that compared the blood pressure-lowering effects of standard vs ICG care. Short-term cost-effectiveness was evaluated as the incremental cost per incremental mm Hg reduced during the trial. Long-term cost-effectiveness was evaluated as incremental cost per quality-adjusted life-year gained over 10 years. ICG care short-term cost-effectiveness was 20 US dollar per incremental mm Hg reduced for systolic blood pressure (vs standard care, 36 US dollar per mm Hg reduced) and 23 US dollar per incremental mm Hg reduced for diastolic blood pressure (vs standard care, 79 US dollar per mm Hg reduced). In the long term, ICG resulted in a 476 US dollar cost savings and 0.109 quality-adjusted life-years gained per patient (-4,371 US dollar per quality-adjusted life-year gained, sensitivity analysis -8,764 to 13,163 US dollar). The use of ICG testing to reduce blood pressure in uncontrolled hypertensive patients is cost-effective from both a short- and long-term perspective.
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