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Related Concept Videos

Nephrons01:10

Nephrons

The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma happens...

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Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
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Segmental multicystic dysplastic kidney in children.

Evelyne Kalyoussef1, Jonathan Hwang, Vinay Prasad

  • 1Division of Urology, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA.

Urology
|November 11, 2006
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Summary

Segmental multicystic dysplastic kidney, a rare condition, typically affects infants. This report details the first adolescent case, expanding understanding of pediatric kidney disease.

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Area of Science:

  • Pediatric Nephrology
  • Urology
  • Medical Genetics

Background:

  • Multicystic dysplastic kidney (MCDK) disease is a congenital anomaly of the kidney and urinary tract.
  • Segmental MCDK is an exceptionally rare subtype, with limited documented cases.
  • Previous literature exclusively reported infantile presentations of segmental MCDK.

Observation:

  • This study presents the first documented case of segmental MCDK in an adolescent female.
  • The patient's clinical presentation and diagnostic findings are detailed.
  • A comprehensive review of the 18 previously reported cases is included.

Findings:

  • The adolescent presentation challenges the typical infantile diagnosis paradigm for segmental MCDK.
  • This case expands the known age range for segmental MCDK.
  • Analysis of published reports provides insights into the natural history and potential variations of the condition.

Implications:

  • Highlights the importance of considering segmental MCDK in adolescents presenting with relevant symptoms.
  • Contributes to a better understanding of the spectrum of pediatric kidney malformations.
  • Informs diagnostic and management strategies for rare congenital kidney anomalies.