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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Mutations01:39

Mutations

Overview
Mutations01:35

Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: Jul 18, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

[Non-hereditary photodermatoses in childhood].

H Ott1, J M Baron

  • 1Klinik für Dermatologie und Allergologie, Universitätsklinikum Aachen, Pauwelsstrasse 30, 52074 Aachen. hagen.ott@post.rwth-aachen.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|November 11, 2006
PubMed
Summary

Childhood photodermatoses significantly impact quality of life. Early diagnosis, effective therapy, and stringent, age-adapted prophylaxis are crucial for preventing recurrence and long-term complications of these UV-associated disorders.

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Area of Science:

  • Dermatology
  • Pediatrics
  • Photomedicine

Context:

  • Acquired UV-associated disorders, including non-hereditary photodermatoses and idiopathic light eruptions, are common in children.
  • These conditions frequently lead to a significant reduction in the quality of life for both affected children and their parents.

Purpose:

  • To emphasize the importance of medical specialists being well-versed in acquired UV-associated disorders.
  • To highlight the necessity of prompt diagnosis and effective treatment strategies.
  • To underscore the need for preventative measures against recurrence and potential long-term complications.

Summary:

  • Childhood photodermatoses are frequently encountered, causing substantial quality of life impairment.
  • Prompt recognition and management by relevant medical specialties are essential.
  • Preventing recurrence through strict, age-appropriate patient and parental education is paramount for mitigating long-term risks.

Impact:

  • Ensuring timely and accurate diagnosis of photodermatoses in pediatric patients.
  • Improving therapeutic outcomes and patient quality of life.
  • Reducing the incidence of recurrent photodermatoses and their associated long-term health consequences.