[The use of immunochemical reactions in determining a cytological diagnosis]

Cytologic preparations of 56 samples of pleural fluid, of 31 samples of ascitic fluid, and 13 puncture biopsy specimens were examined in immunocytochemical tests. Carcinoembryonic antigen and trophoblastic beta 2-globulin were detected in the cytograms. Antibodies to carcinoembryonic antigen and trophoblastic beta 2-globulin employed in the tests did not react with the cells from benign exudation, because tumor cells, particularly glandular carcinoma ones, contain these markers in high concentrations.