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Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts
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Development of a Friedel-Crafts triflation

Marc A Grundl1, Anne Kaster, Ellen D Beaulieu

  • 1Department of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, USA.

Organic Letters
|November 17, 2006
PubMed
Summary

Researchers developed a new Friedel-Crafts reaction variant producing 3-aryl enol triflates. This practical, atom-economical method efficiently synthesizes compounds using electron-rich arenes.

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