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Rat mast cells inhibit platelet aggregation by releasing a nitric oxide-like factor: influence of histamine release
P F Mannaioni1, E Masini, A Pistelli
1Department of Preclinical and Clinical Pharmacology, Florence, Italy.
Abstract:
In th present paper we report the ability of rat serosal mast cells (MC) to release a nitric oxide (NO)-like factor by the inhibition of platelet aggregation and the effect of sodium nitroprusside (NaNP, a NO-generating drug) on MC histamine release by different stimuli.