Related Experiment Video
Updated: Jul 18, 2026
13:12
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
Cognitive functions in brain tumor patients.
1Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA. corread@mskcc.org
Hematology/Oncology Clinics of North America
|November 23, 2006
Summary
Many brain tumor patients face cognitive dysfunction impacting quality of life, but its incidence remains unknown. Future neuro-oncology trials must systematically measure cognitive outcomes to understand tumor and treatment effects.
Area of Science:
- Neuro-oncology
- Clinical Neurology
- Brain Tumor Research
Background:
- Effective cancer treatments increase survival rates for brain tumor patients.
- Cognitive dysfunction is increasingly recognized as a significant issue in brain tumor survivors.
- Current cognitive deficits impact patients' quality of life and daily functioning.
Purpose of the Study:
- To highlight the lack of systematic investigation into the incidence of cognitive dysfunction in brain tumor patients.
- To emphasize the need for cognitive outcome measures in future neuro-oncology clinical trials.
Main Methods:
- This study is a review and commentary on the current state of knowledge regarding cognitive dysfunction in brain tumor patients.
- It identifies a gap in systematic investigation of cognitive impairment incidence.
- It proposes future research directions.
Main Results:
- The incidence of cognitive dysfunction in brain tumor patients is currently unknown due to a lack of systematic investigation.
- Cognitive difficulties persist despite adequate disease control and negatively affect patients' quality of life.
Conclusions:
- Systematic prospective studies incorporating cognitive outcome measures are essential in neuro-oncology.
- Understanding the contribution of the tumor itself and the long-term effects of treatment is crucial for managing cognitive dysfunction.
![Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58641.jpg&w=3840&q=50)
Related Concept Videos
01:14Role of Cerebellum and Prefrontal Cortex in Memory
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...
01:14Brain Imaging
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
01:28Traumatic Brain Injury l: Introduction
DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
01:26Higher Mental Functions of Brain: Learning and Memory
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or playing an...
01:31Organization of the Brain
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
01:15Functional Brain Systems: Limbic System
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...