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Updated: Jul 18, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
[Primary cytomegalovirus infection and thrombophlebitis/pulmonary embolism]
Jakob Gjesing Welinder1, Marianne Kirsten Orholm, Blenda Böttiger
1Statens Serum Institut, Virologisk Afdeling. jwelinder@dadlnet.dk
Abstract:
A young woman was admitted to hospital with suspected pyelonephritis. Due to prolonged fever, further investigations were done and showed a thrombosis in her femoral vein; X-ray and lung scintigraphy revealed a pulmonary embolism. Blood tests showed lymphocytosis, and a primary cytamegalovirus (CMV) infection was confirmed by serology and PCR. The patient was a smoker and obese and was taking oral contraceptives; a factor V Leiden mutation was also found. Deep-vein thrombosis is a rare but severe complication of a primary CMV infection that is also seen in immunocompetent persons.
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