Related Experiment Video
Updated: Jul 18, 2026
07:59
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
A novel bieremophilanolide from Ligularia lapathifolia
Yun-Sen Li1, Shao-Shun Li, Zheng-Tao Wang
1Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, PR China. sinodlsia@yahoo.com
Natural Product Research
|November 28, 2006
Summary
A novel compound, 8,8'-bi-3beta-angeloyloxy-eremophil-7(11)-en-12,8alpha(14beta,6alpha)-diolide, was identified from Ligularia lapathifolia. This discovery expands the known chemical diversity of eremophilanolides found in medicinal plants.
Area of Science:
- Natural Product Chemistry
- Phytochemistry
- Organic Chemistry
Background:
- Ligularia lapathifolia is a plant species known for its potential medicinal properties.
- Eremophilanolides are a class of sesquiterpenoids with diverse biological activities.
Purpose of the Study:
- To isolate and characterize novel chemical constituents from Ligularia lapathifolia.
- To elucidate the structure of a newly discovered eremophilanolide.
Main Methods:
- Extraction of compounds from the roots and rhizomes of Ligularia lapathifolia.
- Structure elucidation using spectroscopic techniques including Infrared (IR) spectroscopy, Mass Spectrometry (MS), and Nuclear Magnetic Resonance (NMR) (1D and 2D).
Main Results:
- Isolation of a new bieremophilanolide, designated as compound 1.
- The structure of compound 1 was determined to be 8,8 -bi-3beta-angeloyloxy-eremophil-7(11)-en-12,8alpha(14beta,6alpha)-diolide.
Conclusions:
- A new eremophilanolide derivative was successfully isolated and structurally characterized.
- This finding contributes to the understanding of the chemical constituents of Ligularia lapathifolia and the eremophilanolide class.
