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Lack of association between prostate-specific acid phosphatase RFLP genotypes and prostatic cancer or benign
S Leskelä1, P Virkkunen, O Lukkarinen
1Biocenter University of Oulu, Finland.
Cytogenetics and Cell Genetics
|January 1, 1991
Abstract:
We have previously reported the identification and basic characterization of two biallelic TaqI RFLPs, A and B, of the 3' end of the human ACPP locus in an unselected Finnish population (Winqvist et al., 1989). In the present investigation, a similar allelic distribution was observed in patients with prostatic cancer or benign hyperplasia. In addition, it was found that the DNA sequences generating RFLP-B are located further downstream from the RFLP-A sequences.