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Updated: Jul 18, 2026

Optimization of Crystal Growth for Neutron Macromolecular Crystallography
Published on: March 13, 2021
[Solubility and phase transitions in the water-protein-salt system]
Abstract:
The previously derived formulas for the curves corresponding to sol-gel, liquid-liquid, and liquid-solid phase transitions, which correlate the critical molar composition of the water-protein-salt system with individual characteristic features of its component (protein charge z, the number of ions adsorbed v, the function of electrolyte activity A) are presented as curves in ordinary coordinates of protein solubility logS against salt concentration m3. Tendencies in changes in phase transition lines versus the v, z, and v/z ratio have been determined. Correlations of the salting-out curve and the salting-out coefficient with phase transitions are discussed.
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