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Fluorescent studies directed towards the location of abnormal epithelial cells in cervical smears
1Department of Biochemistry and Molecular Biology, School of Biological Sciences, University of Manchester.
Abstract:
Cervical screening is concerned with the search for abnormal epithelial cells in smears prepared from scrapings from the uterine cervix. It is a highly skilled labour intensive operation and automated methods of detecting dyskariotic cells in cervical smears would be helpful. We report a fluorescence method of detecting abnormal cervical cells in smears and biopsies using a probe for guanidinobenzoatase. This approach has the potential for automation.